The DEAD OR ALIVE Tournament Executive Committee and hosts of DEAD OR ALIVE 6, DOATEC, already released the names of the first set of fighters involved in this installment – including the owner of DOATEC, Helena Douglas. Other notable fighters include the eighteenth master of the Mugen Tenshin clan, Hayate, and past DEAD OR ALIVE (DOA) tournament winners; Kasumi of the Mugen Tenshin clan; the ultimate ninja, Ryu Hayabusa; the ever-entertaining host, Zack; and the most recent tournament winner, the scorching soul Jann Lee. Two new locations have been scouted to host key matches in the sixth tournament: the remarkable DOA Colosseum, complete with three bold statues showcasing famous fighting stances, and The Throwdown, a gritty back street where raw unfiltered fighting can take place in its prime. Select locations, such as The Throwdown, allow the live audience to get even closer to the action than ever before – with some unruly fans breaking the rules and pushing fighters back into the center of the ring. Combined with the fan-favorite 'Mass Destruction', where fighters can use the environment in their attacks, this tournament is set to be one of the most entertaining ever hosted by DOATEC.
- Break gauge system: A special attack meter new to the series. Use the break gauge to execute new tactics such as a break blow or a break hold.
- Fatal rush: Fatal rush is a powerful combo attack of up to four neatly animated punches and kicks, making a first-time player look like an expert.
- Fights in Dead or Alive are based on a triangle system: strikes beat throws, throws beat holds and holds beat strikes.