In this latest installment of the wildly popular franchise, players are reacquainted with Leon S. Kennedy, Raccoon City's idealistic rookie cop from Resident Evil 2. In the six years since the destruction of Raccoon City, the U.S. government has been able to destroy the nefarious Umbrella Corporation.

Info from ign.com :

The Wiimote is used to aim a targeting cursor in order to target and fire at your enemies. To reload, you hold down on the B trigger and shake the Wiimote. In case you were wondering, the built-in speaker is being programmed with a reload sound effect.

The Wiimote is also used for close-range attacks. When an enemy approaches, all you have to do is give the Wiimote a little of the shake-shake. The game automatically detects the direction of the enemy and makes Leon perform a knife attack. This move can also be used against trees and barrels.

The rest of the game has also been modified to take account of the Wii's unique controller. Interactive event scenes display the Wii buttons when prompting for input. Some events require that you shake the Wiimote.

The producers of the Wii version revealed to Famitsu that one of their goals is to allow families who play the Wii together to experience Resident Evil. The game will include "Easy" and "Amateur" difficulty settings, selectable from the start, that will make aiming easier and keep your life from depleting too fast.

Even if you're a RE pro, you'll probably want to take a look at the Wii version, especially if you didn't try out the PS2 version of the game. All the bonus elements that made it into the PS2 version are being included in the Wii release. That includes the "The Another Order" sequence, where you play as Ada.